MouseModel相关论文
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Coxsackievirus B1 (CVB 1) is a leading causative agent of severe infectious diseases in humans and has been reported to ......
Polymerase chain reaction-based assays facilitate the breeding and study of mouse models of Klinefel
Klinefelter syndrome(KS)is one of the most frequent genetic abnormalities and the leading genetic cause of nonobstructiv......
Overexpression of Twist1 in vascular endothelial cells promotes pathological retinal angiogenesis in
Retinal angiogenesis is a critical process for normal retinal function.However,uncontrolled angiogenesis can lead to pat......
Development of the secondary palate displays molecular heterogeneity along the anterior-posterior axis;however,the under......
Acute Restraint Stress Augments 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine Neurotoxicity via Incre
As an environmental risk factor,psychological stress may trigger the onset or accelerate the progression of Parkinson\......
The intriguing role of fibroblasts and c-Jun in the chemopreventive and therapeutic effect of finast
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Serial observations on an orthotopic gastric cancer model constructed using improved implantation te
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Characterization of gastric cancer models from different cell lines orthotopically constructed using
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Leflunomide,an anti-rheumatoid arthritis drug,controls hyperglycemia by sensitizing insulin receptor
Leflunomide is an immunosuppressive drug prescribed for treating rheumatoid arthritis(RA).Our recent study showed that A......
Fractures are one of the most prevalent clinical conditions worldwide.Among them,cancellous fracture is a major cause of......
Background: The cellular and molecular mechanisms underlying lung allograft rejection remain poorly understood, especial......
Age-dependent neuron loss is associated with impaired adult neurogenesis in forebrain neuron-specifi
Impairment in the microRNA(miRNA)network causes a number of neurodegenerative diseases.Endoribonuclease Dicer is a key R......
Many genetic mouse models of Huntingtons disease(HD)have been created but none fully recapitulate the cardinal phenotype......
The time-dependent changes of the testicular weight and vascular endothelial growth factor expressio
Background: The present research details the expression of vascular endothelial growth factor (VEGF) and pathological ch......
Synergistic function of Kras mutation and HBx in initiation and progression of hepatocellular carcin
Although the activation of Ras pathway is frequently observed in human hepatocellular carcinoma (HCC), the in vivo role ......
Premature ovarian failure (POI) is a main cause of infertility and affects nearly 1% women under 40 years old.It is crit......
The importance of the microenvironment for cancer development, progression and resistance to treatment has recently been......
To elucidate and quantify which cell types contribute to the developing neointima formation causing restenosis after ves......
Objective The incidence of gastric stump cancer is still increasing.Numerous studies using duodenogastric reflux models ......
Mouse model test of extracellular polysaccharide from Candida parapsilosis inhibiting mycelial growt
Objective:To investigate the therapeutical efficacy of extracellular polysaccharide (EPS)from Candida parapsilosis on th......
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Granulocyte colony-stimulating factor ameliorates coronary artery elastin breakdown in a mouse model
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目的通过弹力蛋白酶灌注法构建小鼠腹主动脉瘤模型，为腹主动脉瘤形成相关机制研究提供参考。方法选用C57BL/6野生型小鼠构建猪胰蛋......
目的研究嗜酸性粒细胞信号蛋白4D（SEMA4D）在嗜酸性慢性鼻-鼻窦炎（ECRS）小鼠中的病理作用及意义。方法动物实验：使用曲霉蛋白酶与卵白蛋......
Acute graft-versus-host disease(aGVHD)is caused by allo-activated donor T cells infiltrating target organs.As a regulato......
Metabolomic studies by gas chromatography-orthogonal acceleration time of flight mass spectrometry o
Fulminant hepatic failure (FHF), a liver disorder that often leads to devastating consequences, is one of the most c......
The majority of HCV infection develops chronic infection,which causes steatosis,cirrhosis and hepatocellular carcino......
CRISPR/Cas9 system has recently been exploited for genome engineering.To reduce it down to practice particularly for......
Synergistic function of Kras mutation and HBx in initiation and progression of hepatocellular carcin
Although the activation of Ras pathway is frequently observed in human hepatocellular carcinoma (HCC),the in vivo role o......
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会议
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by anti-nuclear autoantibodies that cause dama......
视网膜变性动物模型是研究人类遗传性视网膜变性疾病治疗的重要工具,目前常用于基础研究的视网膜变性动物模型包括系列视杆细胞变......
本刊编委,武汉市儿童医院检验科向贇(共同第一作者,通讯作者)指导张振等在《Pathogens and Diseases 》(2013,67：184-191,3区,IF=2.......
A novel mouse model for colitis-associated colon carcinogenesis induced by 1,2-dimethylhydrazine and
AIM: To develop an efficient animal colitis-associated carcinogenesis model and to detect the expression of β-catenin a......
AIM: rAAV mediated endostatin gene therapy has been examined as a new method for treating cancer. However,a sustained an......
Objective:To develop a BALB/c mouse model of oral submucous fibrosis (OSF) induced by arecoline and to exhibit an accumu......
目的 观察川芎嗪(TMP)对阿尔茨海默病(AD)模型小鼠学习记忆能力的改善作用及其机制.方法 采用AlCl3灌胃方法建立AD模型小鼠,灌胃给......
